… We introduce a new method for predicting dissociation free energy of subunits by analyzing the structural and topological properties of a protein binding patch on a single subunit of the desired protein complex. The method needs the 3D structure of just one subunit and the information about the position of the intended binding site on the surface of that subunit to predict dimer stability in a classwise manner [full story at JCIM].

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    Holly Quran: “… If you are able to penetrate the provinces of heaven and earth, pass through them! but you shall not pass through except with a power! [wisdom]”

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